Machine Learning Engineer Job at Naderi Engineering, Inc., South San Francisco, CA

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  • Naderi Engineering, Inc.
  • South San Francisco, CA

Job Description

Description

We are looking for talented Machine Learning Engineers to join Prescient Design, a division

devoted to developing structural and machine learning based methods for molecular design

within Genentech’s Research and Early Development (gRED) organization. The successful

candidate will manage projects deploying new techniques for machine learning based molecular

optimization for the analysis and design of small and large molecule drugs within target-driven

design campaigns. Special focus will be given to engineering pipelines for probabilistic

molecular property prediction and Bayesian acquisition for active learning based drug discovery.

Additional activities may extend to include engineering pipelines for molecular generative

modeling.

The Role:

● You will join Prescient Design within the Computational Sciences organization in

gRED. Your peers will be machine learning scientists, engineers, computational

chemists, and computational biologists.

● You will closely collaborate with scientists within Prescient and across gRED.

● You will develop machine learning and Bayesian optimization workflows to analyze

existing, and design new, small and large molecules.

● You will be expected to form close working relationships with small molecule and

protein therapeutic development efforts across the gRED organization.

● You will be expected to work on existing projects and generate new project ideas.

Qualifications:

● PhD degree in a quantitative field (​e.g.​, Computer Science, Chemistry, Chemical

Engineering, Computational Biology, Physics), or MS degree and 3+ years of industry

experience.

● Demonstrated experience with machine learning libraries in production-ready

workflows (e.g., PyTorch + Lightning + Weights and Biases)

● Record of achievement, including at least one high-impact first author publication or

equivalent.

● Excellent written, visual, and oral communication and collaboration skills.

Additional desired qualifications:

● Experience with physical modeling methods (e.g., molecular dynamics) and

cheminformatics toolkits (e.g., rdkit)

● Previous focus on one or more of these areas: molecular property prediction,

computational chemistry, de novo drug design, medicinal chemistry, small molecule

design, self-supervised learning, geometric deep learning, Bayesian optimization,

probabilistic modeling, statistical methods.

● Public portfolio of computational projects (available on e.g. GitHub).

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